Cancer is characterized by unrestrained proliferation and loss of organization, a process that is intimately linked to, and controlled by, reciprocal signaling between the genetically altered tumor epithelium, the stroma, the components of the basement membrane and inflammatory mediators. Much work has been done to characterize the genetics of cancer cells. In this review, we describe the experiments that have been performed, which point to the significant role of the tissue microenvironment in the developmental regulation of normal and neoplastic cells. Using a variety of model systems, the works of a number of laboratories have converged on a hypothesis where the correction of 1 or 2 signaling defects can revert tumor cells to a normal phenotype, both in vivo and in culture, even when the tumor cells possess multiple genetic and epigenetic lesions. This paradigm has been successfully used to treat acute promyelocytic leukemia, and it remains the task of biomedical researchers to identify additional targets for the reversion of other human malignancies.
Fear is the driving force that supports the cancer treatment monopoly. Pharmaceutical companies use fear to keep people coming back for more and more poisonous treatments, because almost all conventional doctors tell their patients that their only chance for survival lies in surgery, radiation, and chemotherapy. It is important to realize that the pharmaceutical cartel wants us to be afraid of cancer. When our fear is great enough, we will surrender our bodies and our lives to the modern healthcare system and say, “I don’t care what you do to me, just kill this cancer!”
For toothaches a clove or drop of clove oil on a cotton ball can be placed on the aching tooth. This method should be used sparingly however and do not place the oil on the gum. For nerve pain a diluted oil up to 3% max can be applied to the skin to treat problems such as shingles. In small doses clove powder can be useful for treating things such as nausea, indigestion, and bloating.
A critical question is often asked: Why pursue the phenotypic reversion of malignancy? Surely it is better to look for more efficient methods of killing tumor cells? Tumors are remarkable creatures, possessed of manifold means to defeat the arsenal of therapeutics arrayed against them. Among other things, the genomic instability of tumors gives them a persistent evolutionary advantage, ensuring the survival of stronger, fitter, more aggressive cells that will go on to populate the body of their host. The approaches that have been taken show that it is possible to revert the malignant phenotype by the correction of environmental cues and by the normalization of signal transduction pathways even as the genome remains malignant and unstable. In this sense, the microenvironment can be dominant over the malignant genotype. It is of course preferable to eradicate the tumor altogether, but aggressive chemotherapy to eradicate a tumor often kills the host. The malleable nature of tumors would indicate that multiple approaches may be necessary. This raises the possibility of the long-term management of some cancers as a chronic condition in which the malignant potential of the tumor cells is constrained, perhaps for the lifetime of the patient.
Ilex paraguariensis Yerba mate It has been claimed to have various effects on human health and these effects have been attributed to the high quantity of polyphenols found in mate tea. Mate contains compounds that act as an appetite suppressant, increases mental energy and focus, and improves mood. Yerba mate also contains elements such as potassium, magnesium, and manganese.