Other research conducted at the same institute studied possible regeneration of the islets of langerhans in rats that were made diabetic for the study and then given gymnema sylvestre leaf extracts. The diabetic rats were able to double the number of their islets and beta cell numbers. Researchers felt that the herbal therapy was able to bring blood sugar stability by repairing the pancreas and increasing insulin secretion.
Collectively, these early experiments demonstrated that factors specific to the environment of the cell were required to attenuate, or to facilitate, the transforming activity of this potent oncogene. Recent work in transgenic models and specialized cell culture systems has begun to define the specific microenvironmental determinants that have the power to normalize overtly malignant cells.
People with type 2 diabetes may use oral medication instead of insulin. Sometimes, people with type 2 can only control their blood sugar with insulin, but it is possible for people with this type to end their need for both insulin and oral medication. Through careful control of diet and establishing and maintaining a healthy weight body mass index (BMI), people can reduce and even reverse type 2 diabetes and its consequences.